Information alert

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This page is for parents and carers whose child is having radiotherapy treatment to a limb (arm or leg). There are several different tumours that may affect a limb. For some children, radiotherapy is used alone and in others chemotherapy may also be used.

This page explains the side effects your child may experience during and after treatment, and how best to cope with them. We understand that this is a worrying time for children and their families. You may feel that you have been given lots of information about your child’s treatment.

We hope this page answers some of your questions surrounding radiotherapy. If you still have any questions or concerns, please ask. We are here for to help.

We want to involve you and your child in all the decisions about their care and treatment. If you decide to go ahead with treatment, by law, we must ask for your consent and will ask you to sign a consent form. This confirms that you agree to your child having the procedure and understand what it involves.

Staff will explain all the risks, benefits, and possible alternatives before they ask you to sign a consent form. If you are unsure about any aspect of your child’s proposed treatment, please do not hesitate to speak to the team looking after your child.

  1. You and your child will see a clinical oncologist who will discuss treatment options with you. You will also meet the paediatric/TYA clinical nurse specialist, specialist paediatric/TYA radiographer and health play specialists
  2. Your child will be consented for radiotherapy or proton beam therapy.
  3. Radiotherapy/Proton Beam treatment planning appointment - Your child will have a planning CT scan using intravenous contrast dye if required. Some children may also require a mask made and an MRI scan.
  4. First treatment - Your child will start treatment 2-3 weeks after the planning scan. Each appointment will take approximately 30-40 minutes.
  5. Review clinics - Your child will be reviewed once a week during treatment. All review clinics are in the radiotherapy and proton beam therapy department and are timed with your child’s treatment.
  6. Treatment complete - Your child will be reviewed by their clinical oncologist 2-3 weeks after treatment has ended. This will either be at Great Ormond Street Hospital, University College Hospital or your child’s referring hospital.

Radiotherapy appointments: All take place in the Radiotherapy Department, basement floor, main UCH hospital building.

Proton Beam Therapy appointments: All take place in the Proton Beam Therapy Department, floors B3 and B4, Grafton Way Building.

Radiotherapy is the specialised treatment of cancer (and some other diseases) using high energy radiation beams. These can either be photons (also called x-rays), electrons or protons. Photons and electrons are delivered from a machine called a linear accelerator whilst protons are delivered from a machine called a cyclotron.

UCLH is one of two NHS proton beam therapy (PBT) centres in the UK, alongside The Christie in Manchester. Proton beam therapy (PBT) is an advanced form of radiotherapy. However, it is not appropriate to treat all paediatric/TYA tumours with proton beam therapy. The most appropriate treatment for your child will be decided by their clinical oncologist and discussed with you.

Radiotherapy does not hurt, and it will not make your child radioactive. They are completely safe to be around siblings, friends, family, and pregnant women. Your child will feel nothing from the treatment and the machine will not touch them. The most important thing is for your child to lie very still for treatment. Lying still can be very difficult for some children and we have health play specialists who will support your child throughout their treatment. However, some children, particularly very young children, will require a general anaesthetic for their treatment.

Treatment is given daily Monday to Friday, including Bank Holidays. A course of treatment can last up to 6 weeks. Your child’s treatment schedule will be decided by their clinical oncologist and confirmed on your first visit to the radiotherapy or proton beam therapy department.

Before beginning radiotherapy or proton beam therapy, your child’s treatment must be carefully planned. Their first visit will be to the radiotherapy or proton planning pre-treatment department. There will be plenty of opportunity to explore what radiotherapy involves for your family. You will meet the team members who will spend time getting to know your child’s needs and how best to support them, and the family, through treatment.

We have a series of short films and photo books that help to explain the different aspects of radiotherapy. This allows children and young people the opportunity to ask questions and to gain an understanding of what radiotherapy is all about. The radiotherapy paediatric team, which includes a specialist paediatric radiographer, a paediatric clinical nurse specialist and radiotherapy health play specialists, will go through step by step what to expect with treatment specific to your child.

Whenever possible, and especially with younger children, we plan separate visits to the mould room, CT scanner and treatment machine in advance of the actual treatment. This is a hands-on experience and questions are encouraged. This ensures your child is comfortable and familiar with what is going to happen.

For more information on preparing your child for radiotherapy treatment you may contact the health play specialists directly on 020 3447 3792.

Radiotherapy for children is an individualised treatment, and any side effects will vary depending on which limb and which part of the limb is being treated, the type of radiotherapy chosen for your child and the radiotherapy dose given. Your child’s clinical oncologist and specialist radiographer will discuss with you how the radiotherapy will affect your child in more detail. However, there will still be plenty of opportunity to talk about anything that you feel needs further discussion.

There are side effects that start during treatment. They gradually get worse during treatment and for a couple of weeks afterwards and then get better after several weeks. Late effects can develop months or years after treatment has ended.

We give radiotherapy treatment in addition to surgery and/or chemotherapy. Patients receiving chemotherapy in addition to radiotherapy may experience more severe or additional side effects to those listed here, depending on the drug regimen used.

The main side effects that occur during radiotherapy treatment are:

Skin changes

The skin in the area being treated will gradually change colour. Your child’s skin will gradually become pink /red or darker, depending on their skin colour. Your child may get some dry peeling of the skin in the treatment area, which may become itchy. Some children may experience peeling of the skin which can be sore. If your child’s skin peels and is sore, they will be referred to the radiotherapy review team for appropriate skin care.

During treatment we advise that your child wash normally using warm water and the soap products they would normally use. Gently pat the skin dry with a soft towel.

The radiotherapy doctors will discuss this with you if it is relevant to your child. Use the moisturiser frequently and gently smooth it on to your child’s skin until it is absorbed. You do not need to wipe the moisturiser off before treatment, but please do not apply moisturiser immediately before their treatment. If your child does not use a moisturiser, speak to the radiographers and they will be able to suggest a few options.

If your child’s skin becomes irritated or peels, stop using the moisturiser. They will be referred to the radiotherapy review team for appropriate skin care.

Avoid exposing the skin in the treatment area to strong sunlight or extreme temperature changes during treatment. After radiotherapy, the skin in the treatment area is always going to be more sensitive to the sun, so it needs to be protected with clothing, and we recommend that you always use a high protection sun cream, Factor 50 or more, on your child’s skin in strong sunlight.

Hair loss

Your child will only lose hair in the area being treated. Hair loss will occur approximately two to three weeks into treatment. Hair might not grow back completely in the areas which have had a very high dose of radiation. Your child’s doctor will advise you if the lost hair is unlikely to regrow.

Swelling of the limb

Your child may experience swelling and tenderness in their limb as treatment progresses. This is due to inflammation of the tissues caused by the radiotherapy. This will settle after treatment has finished, but in a few patients this may persist.

Stiffness

Your child may experience stiffness in their limb. This is due to the radiotherapy causing swelling on the underlying muscle tissue.

Eating and drinking

It is important that your child tries to eat a well-balanced diet and drink plenty of fluids during treatment. Your child will be weighed weekly by the team and if there is any significant weight loss your child will be referred to the dietitian for helpful advice about nutrition. It is important that your child drinks plenty of fluids, between one to two litres a day. This can include water, squash, or hot drinks. This will vary depending upon their individual needs. You will be advised accordingly by the team members.

Tiredness

Tiredness is a very common side effect of treatment. Your child may feel more tired and have less energy than usual, both during and after treatment. Do not worry, this is normal. The tiredness is usually at its worst near the end of treatment and for several weeks afterwards. Allow your child to do as much as they feel they can and rest when they need to. However, gentle exercise has been found to improve energy levels in patients.

Some children do not have a problem with tiredness and should be encouraged to lead a normal life as much as possible. Please tell us if your child is struggling with tiredness. They can be referred to physiotherapy and occupational therapy for practical tips and advice.

Late side effects incurred during treatment can appear to develop months or years after radiotherapy has finished. They are the hardest to accurately predict and, unfortunately, when they do occur, they are usually permanent.

Growth

Radiotherapy will affect the growth of bones and soft tissues in the treated area. In younger children this will mean that the treated limb will be smaller, thinner, or less muscular than the untreated limb.

Swelling of the limb (lymphoedema)

Radiotherapy can increase the risk of swelling in the treated limb. This swelling (also known as lymphoedema) is due to the build-up of lymphatic fluid which flows through lymphatic vessels, which are part of the lymphatic system, which helps to fight infection and maintains a balance of fluids in the body. The chances of lymphoedema happening depend on several factors: the size and position of the tumour, the extent of any surgery your child has had and how much of your child’s limb is treated. The radiotherapy doctors will warn you if it is considered a significant risk for your child.

Fibrosis

Some children may experience long-term fibrosis or thickening of the muscle and tissue that has been treated. The skin in the area being treated may feel “leathery” due to a loss of elasticity and suppleness. Regular stretching exercises, good skin care, the use of water-based moisturisers and sun avoidance can minimise these effects.

Fracture

There is a small risk that the bone in the area treated will be at an increased risk of fracture in later years and there may be problems with healing.

Low bone density (osteopaenia)

Low bone density can occur for several reasons. These can include immobilisation, poor nutrition, low calcium, steroid therapy as well as radiotherapy to the skeleton. Weight bearing exercise, eating a healthy diet and timely hormone replacement therapy can all prevent osteopaenia occurring. Your child will be screened for osteopaenia in the endocrine clinic as he/she grows up.

Second malignancy

Very rarely, children who have received treatment for one particular tumour may develop another type of tumour some years later. The radiotherapy doctors will discuss this with you if it is relevant to your child. Other factors, such as smoking and excess sun exposure may also lead to an increased cancer risk in later life. It is therefore very important that any child who has received this treatment never smokes and always takes precautions against excess sun exposure.

This page deals with the physical aspects of your child’s treatment, but their emotional wellbeing and that of the family is just as important. Having treatment can be deeply distressing for your child and family. Within the radiotherapy department there will be access and support from the specialist paediatric radiographer, play specialists, treatment radiographers and the radiotherapy review team. However, if your child requires further medical or emotional support, they can be referred to a variety of health professionals specialising in children’s and young people’s needs.

Once your child has finished radiotherapy treatment you will be given a follow-up appointment to see the radiotherapy doctors in two to three weeks’ time. This will either be at Great Ormond Street Hospital, University College Hospital or your child’s referring hospital.

Any side effects your child is experiencing will continue for some weeks after treatment has finished. The side effects may become worse before they start to improve. This can be very worrying for families. We expect the side effects to worsen, but please be assured they will gradually settle. Please continue to follow the skin care advice you have been given by the radiotherapy team until your child’s skin returns to normal. Once their skin has fully healed, they can use normal skin care products again.

If you are worried about your child’s skin or any other side effects after their radiotherapy treatment, please call the paediatric clinical nurse specialist or paediatric specialist radiographer for advice. Please see the contact numbers below.

My child’s keyworker is:

Paediatric/TYA Clinical Nurse Specialist
t: 07929 079599

Paediatric/TYA Specialist Therapeutic Radiographer
t: 07817 941313

Radiotherapy Health Play Specialists
t: 07929 834430/ 07929 834428
e: uclh.radiotherapyplayspecialists@nhs.net

Proton Beam Therapy Reception
t: 020 3456 8000/8001

Proton Beam Therapy Review Team (via Proton Beam Therapy Reception)
t: 020 3456 8000/8001

Radiotherapy Reception
t: 020 3447 3700/3701

Radiotherapy Review Team (via Radiotherapy Reception)
t: 020 3447 3700/3701

T11 North Ward
t: 020 3447 1102

T11 North Nurse In Charge (available 24 hours)
t: 07939 788096

T12 North Ward
t: 020 3447 1202

T12 North Nurse In Charge (available 24 hours)
t: 07908 468555

TYA Ambulatory Care (Monday to Friday, 8am to 6.30pm)
t: 020 3447 1837

TYA Ambulatory Care (available 24 hours)
t: 020 3456 7111

If you have any concerns that you would like to discuss in confidence, please contact our PALS (Patient Advice and Liaison Service) for information and advice.
t: 020 3447 3042
e: uclh.pals@nhs.net

Young Lives vs Cancer (formerly CLIC Sargent)
t: 0300 330 0803
w: www.younglivesvscancer.org.uk

Teenage Cancer Trust
t: 020 7612 0370
e: hello@teenagecancertrust.org
w: www.teenagecancertrust.org

Teens Unite
t: 01992 440091
e: info@teensunite.org
w: teensunite.org

Children’s Cancer and Leukaemia Group (CCLG)
e: info@cclg.org.uk
w: www.cclg.org.uk

Children With Cancer UK
t: 0800 222 9000
e: info@childrenwithcancer.org.uk
w: www.childrenwithcancer.org.uk

Macmillan Cancer Support
t: 0808 808 0000
e: cancerline@macmillan.org.uk
w: www.macmillan.org.uk

Cancer Research UK
t: 0808 800 4040
w: www.cancerresearchuk.org

Carers UK
t: 0808 808 7777
e: adviceline@carersuk.org
w: www.carersuk.org

NHS Choices
w: www.nhs.uk

UCLH cannot accept responsibility for information provided by other organisations.

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Page last updated: 21 November 2024

Review due: 30 June 2025