Information alert

If you need a large print, audio, braille, easy-read, age-friendly or translated copy of this page, email the patient information team at uclh.patientinformation@nhs.net. We will do our best to meet your needs.

This information will help you understand your forthcoming treatment and contains answers to many frequently asked questions.

If you have any questions or would like further explanation, please ask one of the team.

Inguinal lymphadenectomy is an operation, performed under a general anaesthetic, to remove lymph nodes from the groins on one or both sides.

The lymphatic system is a part of the body’s immune system which helps to fight infection. It also helps to remove excess fluid from the body. The lymphatic system consists of vessels similar to veins which carry the lymph around the body. Along its course are groups of nodes or glands. After passing through various nodes, the lymph is finally delivered into the blood stream.

  • The lymph nodes usually lie in groups in the neck, armpit and groin. They are also present inside the chest and abdomen. Each group tends to receive lymph from a specific area of the body. The lymph nodes in the groin receive the lymph from the lower half of the body.
  • Sometimes cancer cells can get detached from the main cancer and are carried in the lymph and settle in the lymph nodes. They can grow there, causing swelling. The doctor will have previously examined you to assess if the lymph nodes are affected. You may have had to undergo special investigations such as fine needle aspiration (FNA) cytology, an ultrasound scan and a CT scan.
  • If the lymph nodes are affected by cancer, they are treated with surgery. Sometimes radiotherapy or chemotherapy may be needed. During surgery, the surgeon removes all the nodes from the groin, along with some surrounding tissue. These nodes are sent for examination under microscope and the results are then discussed with you at your follow-up clinic appointment.

There are some risks in having this treatment, which you should consider before consenting for the operation. These potential complications are rare. You should discuss these with your doctor when you visit the hospital.

All operations carry risks, such as bleeding and infection, and these risks will be explained to you in detail before you sign the consent form.

Problems that may occur after groin dissection include:

Pain

You may experience some discomfort following your operation. Please take your painkillers regularly as prescribed on the packet. Do not exceed the stated dose. This discomfort will settle down after a few weeks, but if it does not, please contact your doctor.

Bleeding

You should not experience any major bleeding. It is normal for there to be a spot of blood on the dressing. This can be stopped by applying pressure to the area. Use a clean piece of gauze and press firmly on the wound site for about 10 minutes. If the bleeding does not stop, seek medical advice.

Numbness

Some of this goes away after several months, but the feeling may not return to normal. This may be irritating, but it seldom causes a major problem for most patients.

Inflammation (redness of the skin)

This is a normal and harmless part of the wound healing process and can be confused with infection. It can be accompanied by warmth of the skin and also discomfort or pain, which can be managed with regular painkillers.

Wound breakdown

Your wound may slightly ‘open’ following surgery. Your nurse specialist will advise the appropriate dressings to facilitate wound healing. This will be closely monitored whilst inpatient, dressings may need changing regularly to keep you dry and comfortable whilst in hospital. You will be referred to the community nurses if required upon discharge.

Swelling

This is usually temporary and gradually disappears. Surgery to remove the lymph nodes interferes with the lymphatic system, leading to a build-up of excess fluid in the affected area (known as a seroma). A seroma can feel soft and spongy or hard to touch. It is often uncomfortable, but most need no further treatment and will go in time. If the seroma is too painful, puts pressure on the wound, is red or hot, or you feel unwell, contact your nurse specialist. You may need antibiotics or drainage of the seroma (aspiration), which is a painless procedure and can be performed in the clinic setting.

Genital swelling

You may experience some swelling of the scrotum and penis following your surgery. Supportive underwear such as a scrotal support will help to control this. For more long term genital/pelvic swelling, cycling shorts are advisable following assessment.

Lymphoedema

This type is known as secondary lymphoedema caused by the surgical removal of lymph node from the groins for cancer treatment. As mentioned previously the removal of the nodes interferes with the lymphatic system, therefore swelling occurs as fluid accumulates within the tissues

Signs and symptoms include:

  • Increased swelling of the area (legs)
  • changes in feeling (your leg may feel heavy or stiff difficult to move),
  • skin changes – (firm, more thickened and feeling tight)
  • lymphorrhoea ( leakage of lymph fluid on surface of skin)
  • infection (more risk of cellulitis)

This can occur weeks, months, or years after your cancer treatment. Your CNS will advise you on preventative measures like keeping active i.e. walking, elevating of legs, wearing loss clothing (non-restricting i.e. waist belts) and good skin care. You will also be sign posted to lymphoedema websites for further information.

Post op suction drains (redivac)

This drain is inserted at the end of your operation to ensure adequate drainage of blood and fluid from the operation. You may acquire some leakage around the drain in time as drains tend to stay from one to several weeks.

This can be dealt with using dressings but if it is too high, your nurse specialist may need to cut the drain shorter and place a wound bag over the top of the drain site to collect the fluid.

There are a number of issues that affect the chances of suffering complications, including: age, weight, lifestyle issues and your general state of health. Your anaesthetist and/or your surgeon can give further details. The information below on risks is provided by the Royal College of Anaesthetists:

Very common (1 in 10) and common (1 in 100) side effects

  • feeling sick and vomiting after surgery
  • sore throat
  • dizziness, blurred vision
  • headache
  • itching
  • aches, pains and backache
  • pain during injection of drugs
  • bruising and soreness
  • confusion or memory loss.

Uncommon side effects and complications (1 in 1,000)

  • chest infection
  • bladder problems
  • muscle pains
  • slow breathing (depressed respiration)
  • damage to teeth, lips or tongue
  • an existing medical condition getting worse
  • awareness (becoming conscious during your operation).

Rare (1 in 10,000) or very rare (1 in 100,000 or less) complications

  • damage to the eyes
  • serious allergy to drugs
  • nerve damage
  • death
  • equipment failure.

Deaths caused by anaesthesia are very rare, and are usually caused by a combination of four or five complications together. There are probably about five deaths for every million anaesthetics in the UK.

This is not something we would recommend. Without treatment, the cancer in the lymph nodes will continue to grow and it will spread to other parts of the body. The skin in this area may break down, resulting in an open, painful wound with infection and bleeding.

There may be other types of treatment for your cancer, but your medical team will be suggesting this one, as in their experience they believe it to be the most appropriate for you. Your medical team will be happy to discuss the reasons for recommending this operation and any other concerns you may have.

Surveillance via clinical examination and scans

This is not something we would recommend. Without treatment, the cancer in the lymph nodes will continue to grow and it will spread to other parts of the body. The skin in this area may break down, resulting in an open, painful wound with infection and bleeding.

Sentinel node biopsies

Dynamic sentinel lymph node biopsy is an improved method of detecting whether the nodes in the groin are involved with the tumour and can minimise the extent of groin surgery that is needed, and consequently the potential complications. A dynamic sentinel node biopsy uses a small dose of radioactive material into the sentinel lymph nodes and pictures are taken to detect the location of the sentinel node. If the result of these biopsies is negative, it means you will avoid having to undergo extensive surgery to remove the lymph nodes. An ultrasound scan of your groins would be taken prior to this operation to check for signs of abnormality of the lymph node. Fluid may be taken under ultrasound guidance to check for cancer cells at this time.

This may not be recommended if you have ‘palpable’ nodes (i.e. nodes that the doctor can feel when examining you) when you present to clinic or your ultrasound scan is positive for signs of cancer, as it only involves removing one or two nodes in each groin.

At your pre-operative appointment, the doctors will discuss the surgery with you. Following meeting with the doctors, pre- assessment appointments will also be carried out. These will involve seeing the doctor, anaesthetist, pre-admission nurse and clinical nurse practitioner.

Routine tests, for example bloods, groin ultrasounds and ECGs, may also be performed. This also gives you an opportunity to ask any questions you may have.

At your pre-assessment appointment, you will be told by the nurse or anaesthetist when to stop eating and drinking so you can fast before your operation. You should bring comfortable clothes, something to read and your medicines when you are admitted to hospital.

We want to involve you in all the decisions about your care and treatment. If you decide to go ahead with treatment, legally we must ask you to sign a consent form. This confirms that you agree to have the procedure and understand what it involves. Staff will explain all the risks, benefits and alternatives before they ask you to sign a consent form. If you are unsure about any aspect of your proposed treatment, please don’t hesitate to speak with a senior member of staff again.

An inguinal lymphadenectomy is usually performed at a second stage following surgery to remove the original or primary tumour from around the penis. Occasionally, the groin nodes will be removed at the same time as your primary surgery. This is more common where groin nodes are palpable/prominent at the time of presentation/first appointment.

There are different types of groin dissection, but all have a similar approach. An incision is made to gain access to the lymph nodes in the groin. Skin flaps are carefully lifted up to expose the lymph nodes. All the nodes and some surrounding tissue closely connected with the nodes are removed through a long cut (incision) in the groin. The length of the scar is usually between 6cm and 12cm. The wound is closed with stitches or staples and with one or two drains (plastic tubes) left in place. One end is put in the wound under the skin and the other end is attached to a plastic bag. This drains away any blood or lymph fluid from inside the wound. The surgery usually takes two to three hours.

In a radical inguinal lymphadenectomy, all the lymph nodes seen in the groin are removed. This is a more extensive procedure and, in some patients, a small strip of muscle (sartorius muscle) is used to cover the exposed blood vessels.

In a modified inguinal lymphadenectomy, a group of lymph nodes within a set boundary are removed and analysed while you are still anaesthetised. This is called a ‘frozen section’ and involves the histopathologist having a quick review of the tissue. If there are lymph nodes involved with cancer, the surgeon will proceed to remove all the lymph nodes in the groin (radical inguinal lymphadenectomy).

All the nodes removed will be examined for cancer cells by a specialist pathologist for a final report. This will be the case even if you have undergone frozen section as it is a more detailed analysis. This examination may take several weeks, so you are not likely to receive the results until you attend your follow-up outpatient appointment.

Your team may request that you remain in bed for up to 48 hours after your operation and instructions will be given with regards to how your leg should be positioned.

As mentioned previously at the end of the operation a closed post suction drain is inserted into the groin area. This is a narrow tube sutured to skin which is attached to a closed plastic bottle allows blood and fluid from the operation area to drain out. Drains can stay from one to several weeks – they need to be below 50mls for 2 consecutive days before they can be removed – mobility (walking) encourages good drainage. Often you will be discharged with drains therefore you will be educated on how to manage the drains at home by your nurse specialist and ward team, to ensure you are competent before discharge. You and will receive a weekly follow up with your nurse specialist to review drains and wounds. You will be given a bag

to hold the drain bottle, which is worn across the body to enable you to mobilise more effectively.

You will be given a blood thinning injection to prevent blood clots and you will be required to wear anti embolism stockings which help to encourage leg circulation and help stop you getting blood clots forming. We encourage you to wear the antiembolism stockings for 28 days after surgery. We will also teach you how to administer the blood thinning injection at home once per day for 28 days after surgery.

You will have a urethral catheter (a tube up your water pipe into the bladder to drain urine) in place which will be removed when you are allowed to mobilise.

For the first two days your wound will be covered with a simple dressing. Your team will review the wound on day 2 and will advise the nursing team with regards to future dressings or whether the area can be left exposed.

There will be some pain after the operation. We will give you painkillers both when you are in hospital and to take home with you when you are discharged. The pain will gradually get less over the first week. You will also be given some antibiotics to take home.

The cut in your groin is closed with stitches or skin clips, which are removed about 10-14 days after the operation. You may have these removed in clinic. Should we request removal via your local GP service, a referral will be made on your behalf.

  • Good care of the legs is essential at all times: keep them clean, dry, and well moisturised.
  • Take extra care to avoid scratches and cuts to the leg and insect bites. If any of these happen, keep the wound clean, watch carefully for any sign of infection such as swelling, redness and marked pain, and contact your GP or call NHS 111.
  • Avoid tight belts and socks.
  • Use an electric razor for shaving.
  • Do not walk barefooted.
  • Wear comfortable shoes.
  • Follow your lymphoedema specialist advice and attend appointments.
  • We will ask you to a follow-up outpatient clinic at frequent intervals to monitor any side effects and to detect any possible recurrence of the cancer. You should also examine your groin area regularly every month. If you notice any swelling, please contact your team.

UCLH Macmillan Cancer Information Centre

Location: Cancer Centre Huntley Street

Telephone: 020 3447 8663

Email: uclh.supportandinformation@nhs.net

The Centre provides good quality, comprehensive and appropriate cancer information for anyone affected by cancer. It is staffed by a Macmillan information specialist, supported by cancer nurses and trained volunteers. The service supports patients, their family and friends.

Macmillan Cancer Support

Website: www.macmillan.org.uk

Freefone helpline on 0808 8080 000 (7 days a week 8am - 8pm)

The helpline number is also free from these mobile phone networks: 3, EE, O2, Virgin and Vodafone (when calls are made from the UK).

Cancer Research UK

Website: www.cancerresearch.org.uk

This website provides facts about cancer, including treatment choices.

Lymphoedema service at UCLH

Tel: 020 3447 3925

Email: uclh.lymphoedema.service@nhs.net

Service hours are Monday to Friday, 9am - 5pm.

The Lymphoedema clinic is located on the lower ground floor of the University College Hospital Macmillan Cancer Centre.

RNID typetalk

(Mon-Fri 8.30-5pm)

Email: contact@rnid.org.uk

Telephone: 0808 808 0123

Orchid – fighting male cancer

Website: www.orchid-cancer.org.uk

NHS Direct

Website: https://111.nhs.uk/

Telephone: NHS 111

Other support groups

Penile and urethral Cancer support Group UCLH

These meetings are held first Tuesday of each month except January and August form 12-1.30pm- we offer hybrid sessions so can attend in person or join online – your keyworker will be able to provide more information regarding these valuable meetings.

Penile cancer charity fund via UCLH cancer charity – if you wish to donate or do a fundraiser event then please contact CNS for advise or see details below

Come and see us at: 5th Floor Garden Side, Cancer Centre, Huntley Street, London WC1E 6AG

Mail: 4th Floor, University College Hospital, 235 Euston Road, London NW1 2BU

Telephone: 07971 014127

Email: david.milsom1@nhs.net

See www.patient.co.uk for a list of self-help and support groups for cancer patients

UCLH cannot accept responsibility for information provided by other organisations.

University College at Westmoreland Street Switchboard: 020 3456 7890

For more information you can contact the Clinical Nurse Practitioners as follows:

Sadie Molloy

Mobile: 07852 219 921

Email: uclh.andrologycancercns@nhs.net

Mona Magan Andrology Cancer CNS/keyworker

Mobile: 07929 710 288

Email: Mona.magan2@nhs.net

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Page last updated: 27 February 2025

Review due: 01 March 2027