Professional background

Dr Stubbs is a haematology consultant in haemostasis and thrombosis at UCLH. He undertook his PhD at UCL investigating the genetic basis of immune mediated thrombotic thrombocytopenic purpura (TTP), before taking up his consultant post, sub-specialising in TTP and other TMA.

Other area of interest include general thrombosis, and he runs the general thrombosis clinic at UCLH together with Dr Prasannan. Within the haemostasis and thrombosis team, Dr Stubbs also manages patients with ITP, Cancer-VTE, obstetric haematology and bleeding disorders in conjunction with haemostasis team.

Research interests

  • Haematology
  • Haemostasis and thrombosis
  • TTP
  • Thrombotic microangiopathy

Publications

  • Recombinant ADAMTS13 in Severe Neonatal Thrombotic Thrombocytopenic Purpura, (2022), New England Journal of Medicine, 2022, MJ Stubbs, G Kendall, M Scully
  • Delayed normalization of ADAMTS13 activity in acute thrombotic thrombocytopenic purpura in the caplacizumab era, (2023), Blood, N PrasannanM ThomasM Stubbs et al.
  • Long-term risk of relapse in immune-mediated thrombotic thrombocytopenic purpura and the role of anti-CD20 therapy, Blood, 2023, AJ Doyle, MJ Stubbs et al.
  • Identification of a novel genetic locus associated with immune-mediated thrombotic thrombocytopenic purpura, (2022), Haematologica, MJ Stubbs, P Coppo C Cheshire et al.
  • The use of Obinutuzumab and ofatumumab in the treatment of immune thrombotic thrombocytopenic purpura, (2022), British Journal of Haematology, AJ Doyle, MJ Stubbs, W Lester, et al
  • Vaccine-induced immune thrombocytopenia and thrombosis associated anterior ST-elevation myocardial infarction, (2022), European Heart Journal, J Henry, D Chen, MJ Stubbs, S Bhattacharyya, M Khanji
  • Ischaemic stroke as a presenting feature of ChAdOx1nCoV-19 vaccine-induced immune thrombotic thrombocytopenia, (2021), Journal Neurology, Neurosurgery and Psychiatry, T Al-Mayhani, S Saber, MJ Stubbs et al.
  • Adrenal haemorrhage and infarction in the setting of Vaccine-induced Immune Thrombocytopenia and Thrombosis after SARS-CoV-2 (Oxford-AstraZeneca) vaccination, (2022), A Graf, E Armeni, L Dickinson et al (co-author).
  • Genetic identification of two novel loci associated with steroid sensitive nephrotic syndrome, S Dufek, C Cheshire, AP Levine et al (co-author)
  • Real-world experience with Caplacizumab in the management of acute TTP, (2021), Blood, T Dutt, R Shaw, M Stubbs et al
  • Identification of a homozygous recessive variant in PTGS1 resulting in a congenital aspirin-like defect in platelet function, (2021), Haematologica, M Chan, M Hayman, S Sivapalaratnam et al (co-author)
  • Germline mutations in the transcription factor IKZF5 cause thrombocytopenia, (2019), Blood, C Lentaigne, D Greene et al (co-author)
  • Administration of immunoglobulin G-degrading enzyme of Streptococcus pyogenes (IdeS) for persistent anti-ADAMTS13 antibodies in patients with thrombotic thrombocytopenic purpura in clinic remission, (2019), British Journal of Haematology, MJ Stubbs, M Thomas, C Vendramin et al
  • Comparison of Ritxumab originator (MabThera) to biosimilar (Truxima) in patients with immune-mediated thrombotic thrombocytopenic purpura, (2019), MJ Stubbs, R Low, S McGuckin et al
  • Deep Vein Thrombosis (Review article), (2018), MJ Stubbs, M Mouyis, M Thomas
  • Dengue Fever in returning Travelers. (2015), American Journal Haematology, BJ Bain, MJ Stubbs.
  • Cellular Therapy of Lysosomal Storage Disorders: Current Status and Future Prospects. (2009), Current Pediatric Reviews, R Wynn, MJ Stubbs.
  • Excellent outcome of matched unrelated donor transplantation in paediatric aplastic anaemia following failure with immunosuppressive therapy: A United Kingdom multicentre retrospective experience. (2012), British Journal of Haematology, Volume 157, Issue 3, Pages 339-346, S Samarasinghe, C Steward, P Hiwarkar et al. (Co-author).