Dr Christopher Turner
Telephone:
Email:
Location:
- University College Hospital
- National Hospital for Neurology and Neurosurgery
GMC/GDC number:
4328658
Professional background
Dr Chris Turner graduated from Oxford University and undertook his clinical training in Oxford, Hammersmith Hospital, the Whittington, St George's, Chelsea and Westminster and the National Hospital for Neurology and Neurosurgery.
He was awarded a Wellcome Clinical Research training fellowship in 2000 and completed a PhD in the molecular pathogenesis of Huntington's disease.
In 2007 he became a consultant at the National Hospital for Neurology and Neurosurgery at the MRC Centre for Neuromuscular Diseases. Dr Turner runs neuromuscular clinics at Queen Square.
Dr Turner was appointed as divisional clinical director of Queen Square division in June 2018.
Specialties
Research interests
Dr Turner has a specialist interest in myotonic dystrophy and leads the myotonic dystrophy clinic at Queen Square in conjunction with a clinical nurse specialist, Susan MacDonald.
Publications
1) Turner, C, Ironside, J.W. and Bell, J-E. (1993). Localisation of microglia in CNS amyloid plaques: an immunocytochemical and confocal microscopic study. J. Pathol. 170: p401.
2) Turner, C. (1997) Antisense Therapy: Therapeutic Magic Bullet or Theoretical Dream? Clinical Oncology. Vol.15, No.2, pp.54-58.
3) MacLeod, N, Turner, C, Edgar, J.(1997). Properties of developing lateral geniculate neurones in the mouse. Int. J. Devl. Neuroscience. Vol.15, No.2, pp.205-224.
4) PA Wilkinson, AH Crosby, C Turner, H Patel, NW Wood, AH Schapira, TT Warner. (2003) A Clinical and Genetic Study of SPG5A linked autosomal recessive hereditary spastic paraplegia. Neurology. 61:235-238.
5) Behrendt GC, Tabrizi SJ, Turner C, Levine TS, Sheppard MN. (2003) Idiopathic intimal hyperplasia of small arteries and arterioles affecting intestines and myocardium. Cardiovasc Pathol. Jan-Feb;12(1):32-5.
6) Turner C, Schapira AHV. (2001) Mitochondrial dysfunction in neurodegenerative disorders and ageing. Adv Exp Med Biol. 487:229-51.
7) Turner C. Advances in therapeutic neurology. Practitioner. 2001 Jun;245(1623):551-5.
8) Mosby’s Crash Course in Neurology 2nd and 3rd edns. Eds. Chris Turner , Jeremy Gibbs.
9) Turner C and Schapira AHV. Energy Metabolism and Huntington’s Disease. In: G Bates, P Harper, L Jones (Eds) Huntington’s Disease 3rd edn. Oxford University Press. p309-323. 2002.
10) Turner C and Schapira AHV. Oxidative Stress and Huntington’s Disease. In: J Fuchs, M Podda, L Packer (Eds) Redox Genome Interactions in Health and Disease. 1st edition. Marcel Dekker p439-471.2003.
11) Wilkinson PA, Crosby AH, Turner C, Bradley LJ, Ginsberg L, Wood NW, Schapira AH, Warner TT. A clinical, genetic and biochemical study of SPG7 mutations in hereditary spastic paraplegia. Brain. 2004 127:2148.
12) Strand AD, Aragaki AK, Shaw D, Bird T, Holton J, Turner C, Tapscott SJ, Tabrizi SJ, Schapira AH, Kooperberg C, Olson JM. Gene expression in Huntington's disease skeletal muscle: a potential biomarker. Hum Mol Genet. 2005;14(13):1863-76.
13) P. E. Hart, R. Lodi, B. Rajagopalan, J. L. Bradley, J. G. Crilley, C Turner, A. M. Blamire, D. Manners, P. Styles, A. H. V. Schapira, J. M. Cooper. Antioxidant treatment of Patients with Friedreich’s ataxia: 4 year follow up. Arch Neurol. 2005;62(4):621-6.
14) C Turner and F Schon. Neurological sign: visually-evoked rooting, a fascinating primitive reflex. 2006;6: 358-359.
15) Turner, C, Cooper, JM, Schapira, AHV. Clinical correlates of mitochondrial function in human Huntington’s disease muscle. Movement Disorders. 2007; 22 (12): 1715 - 1721
16) Turner, C. Myasthenia Gravis. Current Anaesthesia and Critical Care. 2007;18(1):15-23.
17) Turner, C. The management of tonic–clonic status epilepticus. Current. Anaesthesia & Critical Care. 2007: 18(2):86-93.
18) Dassan, P, Foster, O, Turner C. Complex Partial Seizures Masquerading as depression. ACNR. July 2007 (online).
19) Medical Masterclass. Neurology, Ophthalmology and Psychiatry. 2nd Edition. Royal College of Physicians. Contributing author.
20) Turner, C and Hilton-Jones, D. The Myotonic Dystrophies: Diagnosis and Management. . J Neurol Neurosurg Psychiatry. 2010 Apr;81(4):358-67.
21) Turner, C and Schapira AH. Mitochondrial matters of the brain: the role in Huntington's disease. J Bioenerg Biomembr. 2010 Jun;42(3):193-8.
22) Turner, C and Schapira AHV. Chapter 17 ‘Disease in muscle and neuromuscular junction’ in Clinical Neurology. 4th Edition. Scadding and Losseff. 2011
23) Turner, C and Schapira AHV. Mitochondrial Disorders. In Bradley's Neurology in Clinical Practice. 6th Edition. 2012.
24) Turner, C and Hilton-Jones, D. “Pharmacological Treatments for Muscle Weakness and Wasting in Myotonic”. Dystrophy. Cochrane Review. (In press).
25) Hilton-Jones D, Bowler M, Lochmueller H, Longman C, Petty R, Roberts M, Rogers M, Turner C, Wilcox D. Modafinil for excessive daytime sleepiness in myotonic dystrophy type 1--the patients' perspective. Neuromuscul Disord. 2012 Jul;22(7):597-603.
26) Turner C, Hilton-Jones D, Lochmüller H, Hanna MG.MRC Centre for Neuromuscular Diseases 1st (1st December 2010), and 2nd (2nd May 2012) myotonic dystrophy workshops, London, UK and the myotonic dystrophy standards of care and national registry meeting, Newcastle, UK July 2011. Neuromuscul Disord. 2013 Dec;23(12):1069-80.
27) Graham CD, Weinman J, Sadjadi R, Chalder T, Petty R, Hanna MG, Turner C, Parton M, Maddison P, Radunovic A, Longman C, Robb Y, Bushby K, Hilton-Jones D, Rose MR. A multicentre postal survey investigating the contribution of illness perceptions, coping and optimism to quality of life and mood in adults with muscle disease. Clin Rehabil. 2013 Nov 15. [Epub ahead of print]
28) Sarkozy A, Hicks D, Hudson J, Laval SH, Barresi R, Hilton-Jones D, Deschauer M, Harris E, Rufibach L, Hwang E, Bashir R, Walter MC, Krause S, van den Bergh P, Illa I, Pénisson-Besnier I, De Waele L, Turnbull D, Guglieri M, Schrank B, Schoser B, Seeger J, Schreiber H, Gläser D, Eagle M, Bailey G, Walters R, Longman C, Norwood F, Winer J, Muntoni F, Hanna M, Roberts M, Bindoff LA, Brierley C, Cooper RG, Cottrell DA, Davies NP, Gibson A, Gorman GS, Hammans S, Jackson AP, Khan A, Lane R, McConville J, McEntagart M, Al-Memar A, Nixon J, Panicker J, Parton M, Petty R, Price CJ, Rakowicz W, Ray P, Schapira AH, Swingler R, Turner C, Wagner KR, Maddison P, Shaw PJ, Straub V, Bushby K, Lochmüller H. ANO5 gene analysis in a large cohort of patients with anoctaminopathy: confirmation of male prevalence and high occurrence of the common exon 5 gene mutation. Hum Mutat. 2013 Aug;34(8):1111-8.
29) Adam R, Leff A, Sinha N, Turner C, Bays P, Draganski B, Husain M. Dopamine reverses reward insensitivity in apathy following globus pallidus lesions. Cortex. 2013 May;49(5):1292-303.
30) Turner C, Hilton-Jones D. Myotonic dystrophy: diagnosis, management and new therapies. Curr Opin Neurol. 2014 Oct;27(5):599-606.
31) Graham CD, Weinman J, Sadjadi R, Chalder T, Petty R, Hanna MG, Turner C, Parton M, Maddison P, Radunovic A, Longman C, Robb Y, Bushby K, Hilton-Jones D, Rose MR. A multicentre postal survey investigating the contribution of illness perceptions, coping and optimism to quality of life and mood in adults with muscle disease. Clin Rehabil. 2014 May;28(5):508-19.
32) Brady S, Barresi R, Charlton R, Turner C, Holton JL. A 29-year-old man with difficulty climbing the stairs. Brain Pathol. 2014 Sep;24(5):549-50.
33) Suetterlin K, Turner C. Diagnosis and management of headache.Br J Hosp Med (Lond). 2014 Dec;75(12):C178-82.
34) Scalco RS, Gardiner AR, Pitceathly RD, Hilton-Jones D, Schapira AH, Turner C, Parton M, Desikan M, Barresi R, Marsh J, Manzur AY, Childs AM, Feng L, Murphy E, Lamont PJ, Ravenscroft G, Wallefeld W, Davis MR, Laing NG, Holton JL, Fialho D, Bushby K, Hanna MG, Phadke R, Jungbluth H, Houlden H, Quinlivan R. CAV3 mutations causing exercise intolerance, myalgia and rhabdomyolysis: Expanding the phenotypic spectrum of caveolinopathies. Neuromuscul Disord. 2016 Aug;26(8):504-10.
35) Neurology: A Queen Square Textbook. Nerve and Muscle disease. Lunn, M, Hanna M, Turner C Riley. September 2016
36) Tan SV, Z'Graggen WJ, Boërio D, Turner C, Hanna MG, Bostock H. In vivo assessment of muscle membrane properties in myotonic dystrophy. Muscle Nerve. 2016 Aug;54(2):249-57.
37) Wood L, Cordts I, Atalaia A, Marini-Bettolo C, Maddison P, Phillips M, Roberts M, Rogers M, Hammans S, Straub V, Petty R, Orrell R, Monckton DG, Nikolenko N, Jimenez-Moreno AC, Thompson R, Hilton-Jones D, Turner C, Lochmüller H.J The UK Myotonic Dystrophy Patient Registry: facilitating and accelerating clinical research. Neurol. 2017 May;264(5):979-988.
38) Neuromuscular Disease Case Studies from Queen Square. Springer. Manji, Turner, Evans. 2017.
39) Germán Morís, Libby Wood, Roberto Fernández-Torrón, Turner C et al. Chronic pain has a strong impact on quality of life in facioscapulohumeral muscular dystrophy: Pain and QoL in FSHD. 2018 Muscle & Nerve 57(3):380-
387
40) A model to predict ventilator requirement in myotonic dystrophy type 1. Vivekananda U, Turner C. Muscle Nerve. 2019 Jun;59(6):683-687.
41) Cardiovascular Manifestations of Myotonic Dystrophy. 2018 In Cardiovascular Genetics and Genomics. Publisher: Springer. Authors: Umesh Vivekananda, Michael Hanna, Chris Turner.
42) Jimenez-Moreno AC, Nikolenko N, Kierkegaard M, Blain AP, Newman J, Massey C, Moat D, Sodhi J, Atalaia A, Gorman GS, Turner C, Lochmüller H. Analysis of the functional capacity outcome measures for myotonic dystrophy.Ann Clin Transl Neurol. 2019 6(8):1487-1497.
43) Jimenez-Moreno AC, Charman SJ, Nikolenko N, Larweh M, Turner C, Gorman G, Lochmüller H, Catt M. Analyzing walking speeds with ankle and wrist worn accelerometers in a cohort with myotonic dystrophy. Disabil Rehabil. 2018 Jul 10:1-7.
44) Landfeldt E, Nikolenko N, Jimenez-Moreno C, Cumming S, Monckton DG, Gorman G, Turner C, Lochmüller H. Disease burden of myotonic dystrophy type 1. J Neurol. 2019 Apr;266(4):998-1006.
45) Consensus-based care recommendations for adults with myotonic dystrophy type 1. Ashizawa T, Gagnon C, Groh WJ, Gutmann L, Johnson NE, Meola G, Moxley R 3rd, Pandya S, Rogers MT, Simpson E, Angeard N, Bassez G, Berggren KN, Bhakta D, Bozzali M, Broderick A, Byrne JLB, Campbell C, Cup E, Day JW, De Mattia E, Duboc D, Duong T, Eichinger K, Ekstrom AB, van Engelen B, Esparis B, Eymard B, Ferschl M, Gadalla SM, Gallais B, Goodglick
T, Heatwole C, Hilbert J, Holland V, Kierkegaard M, Koopman WJ, Lane K, Maas D, Mankodi A, Mathews KD, Monckton DG, Moser D, Nazarian S, Nguyen L, Nopoulos P, Petty R, Phetteplace J, Puymirat J, Raman S, Richer L, Roma E, Sampson J, Sansone V, Schoser B, Sterling L, Statland J, Subramony SH, Tian C, Trujillo C, Tomaselli G, Turner C, Venance S, Verma A, White M, Winblad S. Neurol Clin Pract. 2018 Dec;8(6):507-520.
46) Enrico Bugiardini, Alaa Khan, Rahul Phadke, David S. Lynch, Andrea Cortese, Lucy Feng, Qiang Gang, Alan M. Pittman, Jasper M. Morrow, Chris Turner, Aisling S. Carr, Ros Quinlivan, Alexander M Rossor, Janice Holton, Matt Parton, Julian C Blake, Mary M Reilly, Henry Houlden, Emma Matthews, Michael G. Hanna. Genetic and phenotypic characterisation of inherited myopathies in a tertiary neuromuscular centre. Neuromuscular Disorders (2019) (in press)
47) Chin Yong Kok, Chandra Hoiskote, Hadi Manji, Chris Turner and Alex Rossor. Can compressive thoracic cord lesions cause a pure lower motor neuron cord syndrome? Practical Neurology 2019 Feb;19(1):72-74.
48) Modernising inpatient referral systems: switching from 'on call' to 'online'. Ziff, OJ, Routledge E, Turner C, Chandratheva A. Postgrad Med J. 2019 May;95(1123):292.