Professional background
Professor Adam Rosenthal PhD FRCOG is a consultant gynaecologist, and the lead for colposcopy and familial gynaecological cancer at UCLH.
His clinical interests are gynaecological and anal pre-cancers, colposcopy, high-resolution anoscopy, laparoscopic surgery and inherited (familial) gynaecological cancers. He is also UCL Professor of Gynaecological Cancer Prevention.
He has published extensively on screening for gynaecological cancers and their molecular biology, in journals including the Lancet and the Journal of Clinical Oncology.
He sits on the NHS Cervical Screening Program Research Advisory Committee and the NICE Familial Ovarian Cancer Guideline Committee.
He is a Trustee of the Eve Appeal, the UK's leading gynaecological cancer charity, and medical advisor to various other charities, including Ovacome. An acknowledged international expert on inherited gynaecological cancer, Adam has given interviews on TV and radio on this specialist area.
Specialties
Research interests
Inherited gynaecological cancers, gynaecological cancer screening, anogenital pre-cancer
Publications
Selected from last five years:
- Herzog C, Jones A, Evans I, …, Rosenthal AN, Menon U, Widschwendter M. Plasma cell-free DNA methylation analysis for ovarian cancer detection: Analysis of samples from a case-control study and an ovarian cancer screening trial. Int J Cancer. 2023 Oct 20. doi: 10.1002/ijc.34757. Online ahead of print.
- Bryan SJ, Lee J, Gunu R, …, Rosenthal AN, …, Bhide SA. Circulating HPV DNA as a Biomarker for Pre-Invasive and Early Invasive Cervical Cancer: A Feasibility Study. Cancers (Basel). 2023 May 2;15(9):2590
- Hanson, H., Kulkarni, A., Loong, L., … Rosenthal A.N., … Lalloo, F. (2022). UK consensus recommendations for clinical management of cancer risk for women with germline pathogenic variants in cancer predisposition genes: RAD51C, RAD51D, BRIP1 and PALB2. J Med Genet. 2023 May;60(5):440-449.
- Philpott, S., Raikou, M., Manchanda, R., ... Rosenthal AN. (2022). The avoiding late diagnosis of ovarian cancer (ALDO) project; a pilot national surveillance programme for women with pathogenic germline variants in BRCA1and BRCA2. J Med Genet. 2022 Nov 1:jmedgenet-2022-108741. doi: 10.1136/jmg-2022-108741. Online ahead of print.
- Herzog, C., Marín, F., Jones, A., ... Rosenthal A.N., Bjørge L., Zikan M., Dostalek L., Cibula D., Sundström K., Dillner J., Costas L., Widschwendter, M. (2022). A Simple Cervicovaginal Epigenetic Test for Screening and Rapid Triage of Women With Suspected Endometrial Cancer: Validation in Several Cohort and Case/Control Sets. Journal of Clinical Oncology, doi:10.1200/JCO.22.00266
- Tjandraprawira, K.D., Olaitan, A., Petrie, A., Wilkinson, N., Rosenthal, A.N. (2022). Comparison of Expectant and Excisional/Ablative Management of Cervical Intraepithelial Neoplasia Grade 2 (CIN2) in the Era of HPV Testing. Obstetrics and Gynecology International, 2022 doi:10.1155/2022/7955290
- Dawson, H., Smrke, A., Ellery, P.M., Wilkinson, N., Rosenthal, A.N., McVeigh, T.P. (2022). Fibroadenoma in vulval ectopic breast tissue in a patient with PTEN Hamartoma Tumour Syndrome. Familial Cancer, 21 (3), 363-368. doi:10.1007/s10689-021-00275-9
- Albuquerque, A., Godfrey, M.A.L., Cappello, C., Pesola, F., Bowring, J., Cuming, T., ... Rosenthal, A.N., Sasieni, P., Nathan, M. (2021). Multizonal anogenital neoplasia in women: a cohort analysis. BMC Cancer, 21 (1), doi:10.1186/s12885-021-07949-8
- Cappello, C., Cuming, T., Bowring, J., Rosenthal, A.N., Chindawi, N., Nathan, M. (2020). High-Resolution Anoscopy Surveillance After Anal Squamous Cell Carcinoma: High-Grade Squamous Intraepithelial Lesion Detection and Treatment May Influence Local Recurrence. Diseases of the Colon & Rectum, 63 (10), 1363-1371. doi:10.1097/DCR.0000000000001750
- Yang, X., Song, H., Leslie, G., Engel, C., Hahnen, E., Auber, B., ... Rosenthal, A.N., …Antoniou, A.C. (2020). Ovarian and breast cancer risks associated with pathogenic variants in RAD51C and RAD51D. J Natl Cancer Inst, doi:10.1093/jnci/djaa030
- Crosbie, E.J., Ryan, N.A.J., Arends, M.J., … Rosenthal, A.N., ...Evans, D.G. (2019). The Manchester International Consensus Group recommendations for the management of gynecological cancers in Lynch syndrome.. Genet Med, doi:10.1038/s41436-019-0489-y
- Albuquerque, A., Cappello, C., Cuming, T., … Rosenthal, A.N., Nathan, M. (2018). Anal High-Grade Squamous Intraepithelial Lesions in Pharmacologically Immunocompromised Patients Followed in a Referral Center. Dis Colon Rectum, 61 (11), 1267-1272. doi:10.1097/DCR.0000000000001214
- Albuquerque, A., Sheaff, M., Stirrup, O., ... Rosenthal, A.N., Nathan, M. (2018). Performance of Anal Cytology Compared With High-Resolution Anoscopy and Histology in Women With Lower Anogenital Tract Neoplasia..Clinical Infectious Diseases, doi:10.1093/cid/ciy273
- De-Masi, A., Davis, E., Cuming, T., … Rosenthal, A.N., Nathan, M. (2018). The acceptability of high resolution anoscopy examination in patients attending a tertiary referral centre. BMC Cancer, 18 (1), doi:10.1186/s12885-018-4475-6